Shopping Cart

Your shopping cart is currently empty

Cyclo(Phe-Gly)

Name: Cyclo(Phe-Gly)
Brand: TargetMol
SKU: TN6682
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Synonyms:

Catalog No. TN6682 Copy Product Info

Purity: 99.88%

🥰Excellent

Cyclo(Phe-Gly) is a naturally occurring cyclic dipeptide formed by the cyclization of phenylalanine and glycine. Cyclo(Phe-Gly) exhibits antibacterial, anticancer, and anti-inflammatory activities and is widely found in microbial fermentation broths, as well as in plants and animals. Cyclo(Phe-Gly) can be used in research on microorganisms and tumor mechanisms.

Cas No. 5037-75-2

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
1 mg	$35	-	In Stock
5 mg	$81	-	In Stock
10 mg	$129	-	In Stock
25 mg	$263	-	In Stock
50 mg	$428	-	In Stock
100 mg	$689	-	In Stock
1 mL x 10 mM (in DMSO)	$89	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:99.88%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

In vitro

To discover antagonists of VEGFR2-CD from the fermentation broth produced by streptomyces strain I06A-02832. METHODS AND RESULTS:Under the guidance of ELISA assay against VEGFR2-CD, Compounds 2832 B and 2832 C were isolated and purified by combination of different column chromatographies and HPLC. The structures of compounds 2832 B and C were identified by combination of analysis of UV, IR, MS and 1D-NMR, 2D-NMR. Compounds 2832 B and 2832 C were purified and structurally identified as cyclic dipeptides, and were the same with cyclo-(Pro-Tyr) and Cyclo(Phe-Gly) respectively. Compounds 2832 B and 2832 C showed weak antagonistic activity against VEGFR2-CD by ELISA assay. CONCLUSIONS: They are firstly reported compounds 2832 B and 2832 C had antagonistic activity against VEGFR2-CD.

Chemical Properties

Molecular Weight	204.23
Formula	C₁₁H₁₂N₂O₂
Cas No.	5037-75-2
Smiles	O=C1NC(C(=O)NC1)CC=2C=CC=CC2
Relative Density.	1.202g/cm3
Sequence	cyclo(Phe‑Gly)
Sequence Short	cyclo(FG)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 4 mg/mL (19.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8964 mL	24.4822 mL	48.9644 mL	244.8220 mL
5 mM	0.9793 mL	4.8964 mL	9.7929 mL	48.9644 mL
10 mM	0.4896 mL	2.4482 mL	4.8964 mL	24.4822 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.