L-Aspartic acid 13C is a 13C labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.

L-Aspartic acid demonstrates efficacy as a prodrug for colon-specific drug delivery[1]. Pre-administration of 100 mM L-Aspartic acid and 100 mM L-Glu enhances the retention of L-[3H]Asp in the brain by 206% and 178%, respectively, at the 5-minute mark, while 100 mM D-Asp shows no effect on L-[3H]Asp efflux transport. Conversely, at the 20-minute interval, the retention of L-[3H]Glu is increased by 145% and 156% through co-administration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, with D-Asp again showing no influence. Notably, L-Aspartic acid's efflux rate across the blood-brain barrier (BBB) is observed to be seven times faster than that of L-Glu[2].