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E3 Ligase Ligand-Linker Conjugate

E3 Ligase Ligand-Linker Conjugate is part of PROTACs that contain ligands and junctions for E3 ubiquitin ligases. Upon attachment to the ligand of the target protein, these couplers can be used to construct PROTACs for ubiquitination and degradation of the target protein.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T17925 (S,R,S)-AHPC-PEG2-NH2 2010159-60-9 98%
(S,R,S)-AHPC-PEG2-NH2
(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC ba...
T7758 Thalidomide-O-amido-PEG3-C2-NH2 TFA 1957236-21-3 99.82%
Thalidomide-O-amido-PEG3-C2-NH2 TFA
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-N...
T40002 Pomalidomide-C3-NH2 hydrochloride 2154342-45-5 99.60%
Pomalidomide-C3-NH2 hydrochloride
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
T17924 (S,R,S)-AHPC-PEG2-NH2 hydrochloride 2097973-72-1 99.29%
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochlorid...
T40003 Thalidomide-NH-C6-NH2 hydrochloride 2375194-37-7 99.27%
Thalidomide-NH-C6-NH2 hydrochloride
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
T40025 Pomalidomide-PEG2-CO2H 2140807-17-4 99.25%
Pomalidomide-PEG2-CO2H
Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
T9382 Thalidomide-NH-C2-PEG3-OH 2140807-23-2 99.06%
Thalidomide-NH-C2-PEG3-OH
Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligan...
T40023 Pomalidomide-PEG3-CO2H 2138440-82-9 99.05%
Pomalidomide-PEG3-CO2H
Pomalidomide-PEG3-CO2H (Thalidomide-NH-PEG3-propionic acid) is a synthesized E3 ligase ligand-linker conjugate. Pomalidomide-PEG3-CO2H incorporates the Thalidomi...
T18807 Thalidomide-NH-C4-NH-Boc 2093388-52-2 98.87%
Thalidomide-NH-C4-NH-Boc
Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC ...
T17909 (S,R,S)-AHPC-PEG3-N3 1797406-80-4 98.83%
(S,R,S)-AHPC-PEG3-N3
(S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHP...
T40030 Thalidomide 4'-ether-alkylC2-amine hydrochloride 2341840-99-9 98.56%
Thalidomide 4'-ether-alkylC2-amine hydrochloride
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.
T7760 Thalidomide-O-amido-C3-NH2 TFA 2022182-58-5 98.47%
Thalidomide-O-amido-C3-NH2 TFA
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-C3-NH2 TFA inco...
T9402 Thalidomide-O-C4-NH2 hydrochloride 2376990-29-1 98.33%
Thalidomide-O-C4-NH2 hydrochloride
Thalidomide-linker 9 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC techn...
T17922 (S,R,S)-AHPC-PEG3-NH2 hydrochloride 2097971-11-2 97.58%
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC-based VHL ligan...
T9389 Thalidomide-PEG4-Propargyl 2098799-77-8 97.46%
Thalidomide-PEG4-Propargyl
Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a l...
T40031 Thalidomide-O-C6-NH2 hydrochloride 2245697-88-3 97.45%
Thalidomide-O-C6-NH2 hydrochloride
Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-linke...
T18816 Thalidomide-O-amido-C6-NH2 hydrochloride 2376990-31-5 97.33%
Thalidomide-O-amido-C6-NH2 hydrochloride
Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker....
T40024 Pomalidomide-PEG1-CO2H 2139348-60-8 97.2%
Pomalidomide-PEG1-CO2H
Pomalidomide-PEG1-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
T9401 Thalidomide-NH-PEG1-NH2 hydrochloride 2154342-56-8 97.13%
Thalidomide-NH-PEG1-NH2 hydrochloride
Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-li...
T17325 Pomalidomide-PEG4-C-COOH 2097938-44-6 96%
Pomalidomide-PEG4-C-COOH
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ...
(S,R,S)-AHPC-PEG2-NH2
T17925
(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC ba...
Thalidomide-O-amido-PEG3-C2-NH2 TFA
T7758
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-N...
Pomalidomide-C3-NH2 hydrochloride
T40002
Pomalidomide-C3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
T17924
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochlorid...
Thalidomide-NH-C6-NH2 hydrochloride
T40003
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROT...
Pomalidomide-PEG2-CO2H
T40025
Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
Thalidomide-NH-C2-PEG3-OH
T9382
Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligan...
Pomalidomide-PEG3-CO2H
T40023
Pomalidomide-PEG3-CO2H (Thalidomide-NH-PEG3-propionic acid) is a synthesized E3 ligase ligand-linker conjugate. Pomalidomide-PEG3-CO2H incorporates the Thalidomi...
Thalidomide-NH-C4-NH-Boc
T18807
Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC ...
(S,R,S)-AHPC-PEG3-N3
T17909
(S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHP...
Thalidomide 4'-ether-alkylC2-amine hydrochloride
T40030
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.
Thalidomide-O-amido-C3-NH2 TFA
T7760
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-C3-NH2 TFA inco...
Thalidomide-O-C4-NH2 hydrochloride
T9402
Thalidomide-linker 9 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC techn...
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
T17922
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC-based VHL ligan...
Thalidomide-PEG4-Propargyl
T9389
Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a l...
Thalidomide-O-C6-NH2 hydrochloride
T40031
Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-linke...
Thalidomide-O-amido-C6-NH2 hydrochloride
T18816
Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker....
Pomalidomide-PEG1-CO2H
T40024
Pomalidomide-PEG1-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
Thalidomide-NH-PEG1-NH2 hydrochloride
T9401
Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-li...
Pomalidomide-PEG4-C-COOH
T17325
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ...
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TargetMol