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Guanosine 5'-triphosphate trisodium salt

🥰Excellent
Catalog No. T4969Cas No. 36051-31-7
Alias GTP Trisodium salt, 5'-GTP trisodium salt

Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates signal-transducing G proteins involved in cellular processes such as proliferation, differentiation, and activation of intracellular kinase cascades. It regulates proliferation and apoptosis through the hydrolysis by small GTPases Ras and Rho, and plays a role in vesicle docking, fusion, and formation via Rab. Additionally, GTP serves as an energy-rich precursor for the biosynthesis of DNA and RNA.

Guanosine 5'-triphosphate trisodium salt
Other Forms of Guanosine 5'-triphosphate trisodium salt:

Guanosine 5'-triphosphate trisodium salt

🥰Excellent
Purity: 99.45%
Catalog No. T4969Alias GTP Trisodium salt, 5'-GTP trisodium saltCas No. 36051-31-7
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates signal-transducing G proteins involved in cellular processes such as proliferation, differentiation, and activation of intracellular kinase cascades. It regulates proliferation and apoptosis through the hydrolysis by small GTPases Ras and Rho, and plays a role in vesicle docking, fusion, and formation via Rab. Additionally, GTP serves as an energy-rich precursor for the biosynthesis of DNA and RNA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$42In StockIn Stock
100 mg$58In StockIn Stock
200 mg$97In StockIn Stock
500 mg$197In StockIn Stock
1 g$344In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.45%
Appearance:Solid
Color:White
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates signal-transducing G proteins involved in cellular processes such as proliferation, differentiation, and activation of intracellular kinase cascades. It regulates proliferation and apoptosis through the hydrolysis by small GTPases Ras and Rho, and plays a role in vesicle docking, fusion, and formation via Rab. Additionally, GTP serves as an energy-rich precursor for the biosynthesis of DNA and RNA.
SynonymsGTP Trisodium salt, 5'-GTP trisodium salt
Chemical Properties
Molecular Weight589.13
FormulaC10H13N5Na3O14P3
Cas No.36051-31-7
SmilesO[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([O-])=O)([O-])=O)(O)=O)N2C3=C(C(N=C(N3)N)=O)N=C2.[Na+].[Na+].[Na+]
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 10 mM, Sonication is recommended.
DMSO: Insoluble
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.6974 mL8.4871 mL16.9742 mL84.8709 mL
5 mM0.3395 mL1.6974 mL3.3948 mL16.9742 mL
10 mM0.1697 mL0.8487 mL1.6974 mL8.4871 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitHuman Endogenous MetaboliteGuanosine 5'triphosphate trisodium saltGuanosine 5'-triphosphate trisodiumGuanosine 5'-triphosphateGuanosine 5' triphosphate trisodium saltGTP TrisodiumGTPEndogenousMetaboliteEndogenous Metabolite5'-GTP trisodium5'-GTP
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