Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-hUPF1 Antibody (4P615)

😃Good
Catalog No. TMAC-02076

Anti-hUPF1 Antibody (4P615) is a Rabbit antibody targeting hUPF1. Anti-hUPF1 Antibody (4P615) can be used in WB,ICC,IF,IP,IHC,FCM.

Anti-hUPF1 Antibody (4P615)

Anti-hUPF1 Antibody (4P615)

😃Good
Catalog No. TMAC-02076
Anti-hUPF1 Antibody (4P615) is a Rabbit antibody targeting hUPF1. Anti-hUPF1 Antibody (4P615) can be used in WB,ICC,IF,IP,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4987-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-hUPF1 Antibody (4P615) is a Rabbit antibody targeting hUPF1. Anti-hUPF1 Antibody (4P615) can be used in WB,ICC,IF,IP,IHC,FCM.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC:IF: 1:50-200; IP: 1:10-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIn eukaryotes, it is essential to have the ability to detect and degrade transcripts that lack full coding potential. Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential. Rent1, a mammalian ortholog of Upflp, is essential for embryonic viability. Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase. Rent1 protein has nucleic-acid-dependent ATPase activity and 5' to 3' helicase activity. In addition, Rent1 is an RNA-binding protein whose activity is modulated by ATP and directly interacts with Rent2, which is a mammalian homolog of Upf2p. Two mammalian orthologs to Upf3p, Rent3a and Rent3b, are encoded by two separate genes. Rent3b (also known as Rent3X) is encoded by a X-linked gene and localizes primarily to the nucleus, while Rent 1 and Rent 2 localize primarily in the cytoplasm. Specific Rent3 protein interactions with Y14 and spliced mRNA suggest Rent3a and Rent3b serve as a link between splicing and NMD in the cytoplasm.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human hUPF1 aa 1-200
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 124 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-hUPF1 Antibody (4P615) | purchase Anti-hUPF1 Antibody (4P615) | Anti-hUPF1 Antibody (4P615) cost | order Anti-hUPF1 Antibody (4P615) | Anti-hUPF1 Antibody (4P615) molecular weight