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Anti-Mouse IL-6 Antibody (MP5-20F3)

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Catalog No. T9901A-545

Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE).

Anti-Mouse IL-6 Antibody (MP5-20F3)

Anti-Mouse IL-6 Antibody (MP5-20F3)

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Purity: 95%
Catalog No. T9901A-545
Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$2542-4 weeks2-4 weeks
5 mg$8542-4 weeks2-4 weeks
10 mgPreferential2-4 weeks2-4 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE).
In vivo
Anti-Mouse IL-6 Antibody (MP5-20F3), administered intraperitoneally at a dose of 200 μg (on day 7 and day 14), can significantly reduce the volume of malignant pleural effusion (MPE) in male C57BL/6J mice bearing Lewis lung cancer (LLC) tumors, prolong their survival time, and enhance CD8+ T cell infiltration[1].
Anti-Mouse IL-6 Antibody (MP5-20F3), administered intraperitoneally at a dose of 0.4 mg (once a day, from day 0 to day 5 or day 6), can reduce the hepcidin level to normal in female Balb/c and C57BL/6 mice infected with parasites[2].
Clone
MP5-20F3
Reactivity
Mouse
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-6
Chemical Properties
Molecular Weight150 kDa
Antibody Information
IsotypeRat IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice.

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