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Anti-Mouse IL-6 Antibody (MP5-20F3)

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Catalog No. T9901A-545 Copy Product Info
Purity: 95%
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Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE).

Anti-Mouse IL-6 Antibody
(MP5-20F3)

Pack SizePriceUSA StockGlobal StockQuantity
1 mg$999-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:95.3% (SDS-PAGE); 99.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE).
In vivo
Anti-Mouse IL-6 Antibody (MP5-20F3), administered intraperitoneally at a dose of 200 μg (on day 7 and day 14), can significantly reduce the volume of malignant pleural effusion (MPE) in male C57BL/6J mice bearing Lewis lung cancer (LLC) tumors, prolong their survival time, and enhance CD8+ T cell infiltration[1].
Anti-Mouse IL-6 Antibody (MP5-20F3), administered intraperitoneally at a dose of 0.4 mg (once a day, from day 0 to day 5 or day 6), can reduce the hepcidin level to normal in female Balb/c and C57BL/6 mice infected with parasites[2].
Clone
MP5-20F3
Reactivity
Mouse
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-6
Chemical Properties
Molecular Weight145.19 kDa
Antibody Information
IsotypeRat IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: Anti-Mouse IL-6 Antibody (MP5-20F3) in vivo | Anti-Mouse IL-6 Antibody (MP5-20F3) molecular weight