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Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $254 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $854 | 2-4 weeks | 2-4 weeks | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
| Description | Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE). |
| In vivo | Anti-Mouse IL-6 Antibody (MP5-20F3), administered intraperitoneally at a dose of 200 μg (on day 7 and day 14), can significantly reduce the volume of malignant pleural effusion (MPE) in male C57BL/6J mice bearing Lewis lung cancer (LLC) tumors, prolong their survival time, and enhance CD8+ T cell infiltration[1]. Anti-Mouse IL-6 Antibody (MP5-20F3), administered intraperitoneally at a dose of 0.4 mg (once a day, from day 0 to day 5 or day 6), can reduce the hepcidin level to normal in female Balb/c and C57BL/6 mice infected with parasites[2]. |
| Clone | MP5-20F3 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-6 |
| Molecular Weight | 150 kDa |
| Isotype | Rat IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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