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Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
(Synonyms: SMDF, NRG1-IT2, neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA) Copy Product InfoSynonyms: SMDF, NRG1-IT2, neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA
Catalog No. TMPY-05813 Copy Product Info
Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $112 | 7-10 days | 7-10 days | |
| 10 µg | $183 | 7-10 days | 7-10 days | |
| 20 µg | $306 | 7-10 days | 7-10 days | |
| 50 µg | $492 | 7-10 days | 7-10 days | |
| 100 µg | $842 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | Tag Free |
| Accession Number | Q02297 |
| Construction | A DNA sequence encoding the N-terminal fragment (Ser2-Lys246) of human NRG1 isoform beta1 (Q02297-6) was expressed. The purified protein was biotinylated in vitro. Predicted N terminal: Ser2 |
| Protein Purity | > 75 % as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | SMDF, NRG1-IT2, neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA |
| Research Background | Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis. |
| Molecular Weight | 26.8 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated chemical structure | Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated molecular weight
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