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VEGF165 Protein, Human/Cynomolgus, Recombinant

(Synonyms: VPF, VEGFA, VEGF, Vascular permeability factor, L-VEGF) Copy Product Info

Synonyms: VPF, VEGFA, VEGF, Vascular permeability factor, L-VEGF

Catalog No. TMPY-01041 Copy Product Info
VEGF165 Protein, Human/Cynomolgus, Recombinant is expressed in Baculovirus Insect Cells expression system. The predicted molecular weight is 19.2 kDa and the accession number is P15692-4.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$112-In Stock
10 µg$183-In Stock
20 µg$306-In Stock
50 µg$5177-10 days7-10 days
100 µg$773-In Stock
200 µg$1,1607-10 days7-10 days
500 µg$2,0007-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:≥ 95 % as determined by SDS-PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 3-12 ng/mL.
Description
VEGF165 Protein, Human/Cynomolgus, Recombinant is expressed in Baculovirus Insect Cells expression system. The predicted molecular weight is 19.2 kDa and the accession number is P15692-4.
Species
Human, Cynomolgus
Expression System
Baculovirus Insect Cells
TagTag Free
Accession NumberP15692-4
ConstructionA DNA sequence encoding the human / cynomolgus VEGF165 isoform (P15692-4) (Met1-Arg191) was expressed. Human and Cynomolgus VEGF165 sequences are identical.
Protein Purity
> 97 % as determined by SDS-PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from sterile 100mM Glycine, 10mM NaCl, pH 7.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
ReconstitutionReconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
SynonymsVPF, VEGFA, VEGF, Vascular permeability factor, L-VEGF
Research Background
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.
Chemical Properties
Molecular Weight19.2 kDa (predicted); 20 and 22 kDa (reducing conditions, corresponding to the monomer)
Relative Density.no data available
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: VEGF165 Protein, Human/Cynomolgus, Recombinant chemical structure | VEGF165 Protein, Human/Cynomolgus, Recombinant molecular weight