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Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127)

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Catalog No. TMAC-03360
Alias placental type, Placental alkaline phosphatase 1, ALPP and PLAP, Alkaline phosphatase Regan isozyme, Alkaline Phosphatase

Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127) is a Rabbit antibody targeting Alkaline Phosphatase (Placental type) /ALPP. Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127) can be used in WB,ICC/IF,IHC.

Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127)

Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127)

😃Good
Catalog No. TMAC-03360Alias placental type, Placental alkaline phosphatase 1, ALPP and PLAP, Alkaline phosphatase Regan isozyme, Alkaline Phosphatase
Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127) is a Rabbit antibody targeting Alkaline Phosphatase (Placental type) /ALPP. Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127) can be used in WB,ICC/IF,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127) is a Rabbit antibody targeting Alkaline Phosphatase (Placental type) /ALPP. Anti-Alkaline Phosphatase (Placental type) /ALPP Antibody (8Z127) can be used in WB,ICC/IF,IHC.
Synonymsplacental type, Placental alkaline phosphatase 1, ALPP and PLAP, Alkaline phosphatase Regan isozyme, Alkaline Phosphatase
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of PLAP on human placenta tissue (1) and Hela cell (2) lysate using anti-PLAP antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-PLAP antibody. Counter stained with hematoxylin.
3. ICC staining PLAP in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining PLAP in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundAlkaline phosphatases (AP) are glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+-metallated glycoproteins that catalyze the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. Placental alkaline phosphatase (also known as PLAP, ALPP, PALP, placental ALP-1 or Regan isozyme) is a 530 amino acid, tissue-specific AP that is expressed in the placenta, the serum of pregnant women and ectopically expressed in various cancers, including those of the ovary and testis. PLAP may assist in guiding migratory cells and transporting specific molecules, such as fatty acids and immunoglobulins, across the plasma membrane. The three tissue-specific APs identified in human, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous and their genes are clustered on chromosome 2q.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 70 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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