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Tris(4-aminophenyl)methane

Name: Tris(4-aminophenyl)methane
Brand: TargetMol
SKU: T19073
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19073Cas No. 548-61-8

Alias Leucopararosaniline

Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.

Tris(4-aminophenyl)methane

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Purity: 96.52%

Catalog No. T19073Alias LeucopararosanilineCas No. 548-61-8

Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$29	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:96.52%

Appearance:Solid

Color:Purple

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.
In vitro	Tris(4-aminophenyl)methane shows weak HCV helicase inhibition (30% inhibition at 100 μM) [1].
Cell Research	1. Use as an HCV helicase inhibitor 1. Dissolution: Leucopararosaniline is generally dissolved in DMSO or water, and the specific solvent depends on the experimental requirements. The solubility may be low, so an appropriate concentration needs to be used. 2. Inhibitor concentration: In experiments, the concentration of Leucopararosaniline is usually between 1-10 μM, and the specific concentration needs to be optimized according to experimental conditions. 3. Cell treatment: In the virus infection model, Leucopararosaniline is added to the cell culture and treated for a certain period of time to inhibit HCV helicase and observe its effect on viral replication. 2. Use as a dye: 1. Dissolve it in an appropriate solvent (such as PBS or DMSO), then add it to the experimental system for staining. 2. Specific staining conditions (such as staining concentration, time, etc.) need to be optimized according to experimental requirements. The above information is based on published literature. Experimental procedures should be appropriately modified to meet specific research demands.
Synonyms	Leucopararosaniline

Chemical Properties

Molecular Weight	289.37
Formula	C₁₉H₁₉N₃
Cas No.	548-61-8
Smiles	Nc1ccc(cc1)C(c1ccc(N)cc1)c1ccc(N)cc1
Relative Density.	1.208g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (190.07 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2.5 mg/mL (8.64 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4558 mL	17.2789 mL	34.5578 mL	172.7892 mL
5 mM	0.6912 mL	3.4558 mL	6.9116 mL	34.5578 mL
10 mM	0.3456 mL	1.7279 mL	3.4558 mL	17.2789 mL
20 mM	0.1728 mL	0.8639 mL	1.7279 mL	8.6395 mL
50 mM	0.0691 mL	0.3456 mL	0.6912 mL	3.4558 mL
100 mM	0.0346 mL	0.1728 mL	0.3456 mL	1.7279 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc