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Anti-ABCG5 Polyclonal Antibody is a Rabbit antibody targeting ABCG5. Anti-ABCG5 Polyclonal Antibody can be used in ELISA,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-ABCG5 Polyclonal Antibody is a Rabbit antibody targeting ABCG5. Anti-ABCG5 Polyclonal Antibody can be used in ELISA,WB. |
| Synonyms | STSL, Sterolin 1, ATP binding cassette sub family G(WHITE) member 5(sterolin 1), ATP binding cassette sub family G member 5, ABCG5 |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein (Probable). |
| Tissue Specificity | Strongly expressed in the liver, lower levels in the small intestine and colon. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human ABCG5 |
| Antigen Species | Human |
| Gene Name | ABCG5 |
| Gene ID | |
| Protein Name | ATP-binding cassette sub-family G member 5 |
| Uniprot ID | |
| Biology Area | Metabolism of lipids and lipoproteins,Lipid transport,Cholesterol Metabolism,Cholesterol Metabolism,Lipid metabolism,Cancer,Heart disease,Lipid metabolism |
| Function | Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. |
| Molecular Weight | Theoretical: 72 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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