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ARID1A Protein, Human, Recombinant (His & Myc)

Catalog No. TMPH-00987
Synonyms: Osa homolog 1, BRG1-associated factor 250a, ARID domain-containing protein 1A, hOSA1, ARID1A, SWI-like protein, BRG1-associated factor 250, AT-rich interactive domain-containing protein 1A, BAF250A, C1orf4, SMARCF1, BAF250, OSA1, B120

ARID1A Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 32.4 kDa and the accession number is O14497.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
ARID1A Protein, Human, Recombinant (His & Myc)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 398.00
100 μg 20 days $ 1,370.00
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Biological Description
Technical Params
Product Properties
Description ARID1A Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 32.4 kDa and the accession number is O14497.
Species Human
Expression System Baculovirus Insect Cells
Tag N-10xHis, C-Myc
Accession Number O14497
Synonyms Osa homolog 1, BRG1-associated factor 250a, ARID domain-containing protein 1A, hOSA1, ARID1A, SWI-like protein, BRG1-associated factor 250, AT-rich interactive domain-containing protein 1A, BAF250A, C1orf4, SMARCF1, BAF250, OSA1, B120
Amino Acid SLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMM
Construction 1976-2231 aa
Protein Purity > 85% as determined by SDS-PAGE.
Molecular Weight 32.4 kDa (predicted)
Formulation Tris-based buffer, 50% glycerol
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

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Keywords

ARID1A Protein, Human, Recombinant (His & Myc) Osa homolog 1 BRG1-associated factor 250a ARID domain-containing protein 1A hOSA1 ARID1A SWI-like protein BRG1-associated factor 250 AT-rich interactive domain-containing protein 1A BAF250A C1orf4 SMARCF1 BAF250 OSA1 B120 recombinant recombinant-proteins proteins protein

 

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