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Anti-GPR109A Polyclonal Antibody
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Catalog No. TMAB-00787
Anti-GPR109A Polyclonal Antibody is a Rabbit antibody targeting GPR109A. Anti-GPR109A Polyclonal Antibody can be used in WB.
Anti-GPR109A Polyclonal Antibody
Anti-GPR109A Polyclonal Antibody
😃Good
Catalog No. TMAB-00787
Anti-GPR109A Polyclonal Antibody is a Rabbit antibody targeting GPR109A. Anti-GPR109A Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-GPR109A Polyclonal Antibody is a Rabbit antibody targeting GPR109A. Anti-GPR109A Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Cow,Rabbit) |
| Verified Activity | Sample: Skin (Mouse) Lysate at 40 μg Primary: Anti-GPR109R (TMAB-00787) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 40 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. |
| Immunogen | KLH conjugated synthetic peptide: human GPR109A/HM74A |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Hydrolysis,p53 Pathway,Hydrolysis,Cancer,GPCR |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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