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α-L-Fucopyranos
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Catalog No. T203819Cas No. 6696-41-9
Alias α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-Fucopyranose
α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors.
α-L-Fucopyranos
😃Good
Purity: 99.89%
Catalog No. T203819Alias α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-FucopyranoseCas No. 6696-41-9
α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $692 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock | |
| 100 mg | $1,970 | - | In Stock | |
| 200 mg | $2,690 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.89%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors. |
| In vitro | Methods: RAW264.7 macrophages were treated with α-L-Fucopyranos (5 mg/ml, 10 mg/ml, 4 hours), and the cells were collected to quantify the levels of IL-6 and MCP-1 by qPCR. Results: Quantitative PCR Results showed that the levels of Mcp1 and Il6 decreased in a concentration-dependent manner in RAW264.7 cells (Figure 5C), indicating that α-L-Fucopyranos can alleviate inflammation in vivo and in vitro. [2] |
| In vivo | Methods: α-L-Fucopyranos (100 mg/kg, intraperitoneal injection, three times a week) was used to treat HuCCT-1 cell-transplanted tumor model mice, and tumor volume and body weight were measured daily. Results: Tumor size, angiogenesis, and stiffness index were reduced in the α-L-Fucopyranos-treated group, indicating that α-L-Fucopyranos can inhibit tumor growth in mice. [3] |
| Synonyms | α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-Fucopyranose |
| Molecular Weight | 164.16 |
| Formula | C6H12O5 |
| Cas No. | 6696-41-9 |
| Smiles | O[C@H]1[C@@H](O)[C@H](O)[C@H](O)O[C@H]1C |
| Storage | store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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