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α-L-Fucopyranos
🥰Excellent
Catalog No. T203819Cas No. 6696-41-9
Alias α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-Fucopyranose
α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors.
α-L-Fucopyranos
🥰Excellent
Purity: 99.89%
Catalog No. T203819Alias α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-FucopyranoseCas No. 6696-41-9
α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $483 | In Stock | |
| 10 mg | $692 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,970 | In Stock | |
| 200 mg | $2,690 | In Stock |
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Purity:99.89%
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Product Introduction
Bioactivity
Chemical Properties
| Description | α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors. |
| In vitro | Methods: RAW264.7 macrophages were treated with α-L-Fucopyranos (5 mg/ml, 10 mg/ml, 4 hours), and the cells were collected to quantify the levels of IL-6 and MCP-1 by qPCR. Results: Quantitative PCR Results showed that the levels of Mcp1 and Il6 decreased in a concentration-dependent manner in RAW264.7 cells (Figure 5C), indicating that α-L-Fucopyranos can alleviate inflammation in vivo and in vitro. [2] |
| In vivo | Methods: α-L-Fucopyranos (100 mg/kg, intraperitoneal injection, three times a week) was used to treat HuCCT-1 cell-transplanted tumor model mice, and tumor volume and body weight were measured daily. Results: Tumor size, angiogenesis, and stiffness index were reduced in the α-L-Fucopyranos-treated group, indicating that α-L-Fucopyranos can inhibit tumor growth in mice. [3] |
| Synonyms | α-L-Fucose, Deoxy-a-L-galactopyranose, Alpha-L-Fucose, Alpha-L-Fucopyranose |
| Molecular Weight | 164.16 |
| Formula | C6H12O5 |
| Cas No. | 6696-41-9 |
| Smiles | O[C@H]1[C@@H](O)[C@H](O)[C@H](O)O[C@H]1C |
Storage & Solubility Information
| Storage | store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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