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GADD45G Protein, Human, Recombinant (His)

Catalog No. TMPJ-00711
Synonyms: Cytokine-Responsive Protein CR6, Growth Arrest and DNA Damage-Inducible Protein GADD45 Gamma, Growth Arrest and DNA Damage-Inducible Protein GADD45 γ, DDIT-2, DNA Damage-Inducible Transcript 2 Protein, CR6, DDIT2, GADD45G

Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apoptosis. GADD45G inhibits cell growth and differentiation by androgens. The mRNA expression is down-regulated in hepatocellular carcinoma.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
GADD45G Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apoptosis. GADD45G inhibits cell growth and differentiation by androgens. The mRNA expression is down-regulated in hepatocellular carcinoma.
Species Human
Expression System E. coli
Tag N-6His
Accession Number O95257
Synonyms Cytokine-Responsive Protein CR6, Growth Arrest and DNA Damage-Inducible Protein GADD45 Gamma, Growth Arrest and DNA Damage-Inducible Protein GADD45 γ, DDIT-2, DNA Damage-Inducible Transcript 2 Protein, CR6, DDIT2, GADD45G
Amino Acid Met1-Glu159
Construction Recombinant Human Growth Arrest And DNA Damage-Inducible Protein GADD45 Gamma is produced by our E.coli expression system and the target gene encoding Met1-Glu159 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 21 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apoptosis. GADD45G inhibits cell growth and differentiation by androgens. The mRNA expression is down-regulated in hepatocellular carcinoma.

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Keywords

GADD45G Protein, Human, Recombinant (His) CR-6 Cytokine-Responsive Protein CR6 Growth Arrest and DNA Damage-Inducible Protein GADD45 Gamma Growth Arrest and DNA Damage-Inducible Protein GADD45 γ DDIT-2 DNA Damage-Inducible Transcript 2 Protein CR6 CR 6 DDIT2 GADD45G DDIT 2 recombinant recombinant-proteins proteins protein

 

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