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Anti-APC Antibody (8V676)

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Catalog No. TMAC-00237

Anti-APC Antibody (8V676) is a Rabbit antibody targeting APC. Anti-APC Antibody (8V676) can be used in WB,ICC,IP.

Anti-APC Antibody (8V676)

Anti-APC Antibody (8V676)

😃Good
Catalog No. TMAC-00237
Anti-APC Antibody (8V676) is a Rabbit antibody targeting APC. Anti-APC Antibody (8V676) can be used in WB,ICC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Anti-APC Antibody (8V676) is a Rabbit antibody targeting APC. Anti-APC Antibody (8V676) can be used in WB,ICC,IP.
Ig Type
IgG
Reactivity
Human,Rat
Application
Recommended Dose
WB: 1:1000-5000; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner??s syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2,843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. β-catenin and γ-catenin (also called plakoglobin), are involved in the regulation of cellular adhesion. APC and E-cadherin compete for binding to specific internal regions of both β- and γ-catenin. Interactions between cytoskeleton and the APC, E-cadherin, β/γ catenin complex are mediated by α-catenin.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 160 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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