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Anti-APC Antibody (8V676) (Synonyms: Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli...)
Catalog No. TMAC-00237 Copy Product Info
🥰Excellent
Anti-APC Antibody (8V676) is a Rabbit antibody targeting APC. Anti-APC Antibody (8V676) can be used in ICC,IP,WB.
Anti-APC Antibody (8V676)
Copy Product Info🥰Excellent
Catalog No. TMAC-00237
Synonyms Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli protein
Anti-APC Antibody (8V676) is a Rabbit antibody targeting APC. Anti-APC Antibody (8V676) can be used in ICC,IP,WB.
Anti-APC Antibody
(8V676)
(8V676)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-APC Antibody (8V676) is a Rabbit antibody targeting APC. Anti-APC Antibody (8V676) can be used in ICC,IP,WB. |
| Synonyms | Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli protein |
| Ig Type | IgG |
| Clone | 8V676 |
| Reactivity | Human,Rat |
| Verified Activity | 1. Western blot analysis of APC on mouse brain lysates using anti-APC antibody at 1/1,000 dilution. 2. ICC staining APC in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining APC in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.    |
| Application | |
| Recommended Dose | WB: 1:1000-5000; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner??s syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2,843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. β-catenin and γ-catenin (also called plakoglobin), are involved in the regulation of cellular adhesion. APC and E-cadherin compete for binding to specific internal regions of both β- and γ-catenin. Interactions between cytoskeleton and the APC, E-cadherin, β/γ catenin complex are mediated by α-catenin. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 160 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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