C1orf33/MRTO4 Protein, Human, Recombinant (His)

Catalog No. TMPY-03751

MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. MRTO4 is a nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. The precise function of MRTO4 is currently unknown. It appears to be involved in mRNA turnover and ribosome assembly. MRTO4 is widely expressed in the appendix, lymph node, and other tissues. Diseases associated with MRTO4 include Bacterial Conjunctivitis and Robinow Syndrome, Autosomal Dominant 1.

C1orf33/MRTO4 Protein, Human, Recombinant (His)

Catalog No. TMPY-03751

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100 μg	$812	7-10 days

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Biological Activity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. MRTO4 is a nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. The precise function of MRTO4 is currently unknown. It appears to be involved in mRNA turnover and ribosome assembly. MRTO4 is widely expressed in the appendix, lymph node, and other tissues. Diseases associated with MRTO4 include Bacterial Conjunctivitis and Robinow Syndrome, Autosomal Dominant 1.
Species	Human
Expression System	E. coli
Tag	N-His
Accession Number	Q9UKD2
Synonyms	MRT4 homolog, ribosome maturation factor,MRT4,dJ657E11.4,C1orf33
Construction	A DNA sequence encoding the human MRTO4 (Q9UKD2) (Met1-Asp239) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
Protein Purity	> 95 % as determined by SDS-PAGE
Molecular Weight	29.4 kDa (predicted); 32 kDa (reducing conditions)
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. MRTO4 is a nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. The precise function of MRTO4 is currently unknown. It appears to be involved in mRNA turnover and ribosome assembly. MRTO4 is widely expressed in the appendix, lymph node, and other tissues. Diseases associated with MRTO4 include Bacterial Conjunctivitis and Robinow Syndrome, Autosomal Dominant 1.