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Bis-Mal-PEG11, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis-Mal-PEG11, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two distinct ligands linked by a connector—one binding an E3 ubiquitin ligase and the other targeting a specific protein—utilize the intracellular ubiquitin-proteasome system for selective protein degradation [1]. |
Molecular Weight | 846.92 |
Formula | C38H62N4O17 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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