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Palmitoyl serinol

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Catalog No. T60957Cas No. 126127-31-9
Alias N-Palmitoyl serinol

Palmitoyl serinol (N-Palmitoyl serinol), an analog of the endogenous cannabinoid N-palmitoylethanolamine, significantly stimulated an IL-4-mediated decrease in cellular ceramide levels in human epidermal keratinocytes (KC). Palmitoyl serinol stimulates the production of specific ceramide species and neurotransmitters through an endogenous cannabinoid receptor CB1-dependent mechanism. production of specific ceramide species as well as the total amount of ceramide.

Palmitoyl serinol

Palmitoyl serinol

😃Good
Catalog No. T60957Alias N-Palmitoyl serinolCas No. 126127-31-9
Palmitoyl serinol (N-Palmitoyl serinol), an analog of the endogenous cannabinoid N-palmitoylethanolamine, significantly stimulated an IL-4-mediated decrease in cellular ceramide levels in human epidermal keratinocytes (KC). Palmitoyl serinol stimulates the production of specific ceramide species and neurotransmitters through an endogenous cannabinoid receptor CB1-dependent mechanism. production of specific ceramide species as well as the total amount of ceramide.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$14235 days35 days
10 mg$28235 days35 days
50 mg$1,13035 days35 days
100 mg$1,98035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Description
Palmitoyl serinol (N-Palmitoyl serinol), an analog of the endogenous cannabinoid N-palmitoylethanolamine, significantly stimulated an IL-4-mediated decrease in cellular ceramide levels in human epidermal keratinocytes (KC). Palmitoyl serinol stimulates the production of specific ceramide species and neurotransmitters through an endogenous cannabinoid receptor CB1-dependent mechanism. production of specific ceramide species as well as the total amount of ceramide.
In vitro
Palmitoyl serinol promotes ceramide production through a CB1-dependent mechanism in an in vitro model of skin inflammation. [1]
SynonymsN-Palmitoyl serinol
Chemical Properties
Molecular Weight329.52
FormulaC19H39NO3
Cas No.126127-31-9
SmilesO=C(NC(CO)CO)CCCCCCCCCCCCCCC
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

CannabinoidReceptorCannabinoid Receptor
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