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Anti-LAMP3/CD208 Antibody (3R433) (Synonyms: lysosomal associated membrane protein 3, LAMP3)

Name: Anti-LAMP3/CD208 Antibody (3R433)
Brand: TargetMol
SKU: TMAY-00947
Rating: 4.5 (1 reviews)

Catalog No. TMAY-00947 Copy Product Info

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Anti-LAMP3/CD208 Antibody (3R433) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (3R433) can be used in ICC/IF.

Anti-LAMP3/CD208 Antibody (3R433)

Copy Product Info

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Catalog No. TMAY-00947

Synonyms lysosomal associated membrane protein 3, LAMP3

Anti-LAMP3/CD208 Antibody (3R433) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (3R433) can be used in ICC/IF.

Anti-LAMP3/CD208 Antibody
(3R433)

Pack Size	Price	USA Stock	Global Stock	Quantity
20 μL	$94	7-10 days	7-10 days
100 μL	$269	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-LAMP3/CD208 Antibody (3R433) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (3R433) can be used in ICC/IF.
Synonyms	lysosomal associated membrane protein 3, LAMP3
Ig Type	Rabbit IgG
Clone	3R433
Reactivity	Human
Specificity	Human LAMP3/CD208
Verified Activity	Immunofluorescence staining of Human LAMP3 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human LAMP3 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and countstained with DAPI (blue). Positive staining was localized to cytoplasm.
Application	ICC/IF
Recommended Dose	ICC-IF: 1:20-1:100
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human CD208 / DC-LAMP / LAMP3 (rh CD208 / DC-LAMP / LAMP3; TMPY-01013; NP_055213.2; Lys28-Thr381).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human CD208 / DC-LAMP / LAMP3 protein (TMPY-01013)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Keywords

LAMP-3LAMP 3

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