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VPC-14228

Name: VPC-14228
Brand: TargetMol
SKU: T24943
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T24943Cas No. 19983-28-9

Alias VPC14228, VPC 14228

VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.

VPC-14228

🥰Excellent

Purity: 99.96%

Catalog No. T24943Alias VPC14228, VPC 14228Cas No. 19983-28-9

VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$33	In Stock	In Stock
5 mg	$89	In Stock	In Stock
10 mg	$146	In Stock	In Stock
25 mg	$313	In Stock	In Stock
50 mg	$497	In Stock	In Stock
100 mg	$693	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$87	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.96%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
Synonyms	VPC14228, VPC 14228

Chemical Properties

Molecular Weight	246.33
Formula	C₁₃H₁₄N₂OS
Cas No.	19983-28-9
Smiles	C1CN(CCO1)C1=NC(=CS1)C1=CC=CC=C1
Relative Density.	1.227 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (223.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.12 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0596 mL	20.2980 mL	40.5959 mL	202.9797 mL
5 mM	0.8119 mL	4.0596 mL	8.1192 mL	40.5959 mL
10 mM	0.4060 mL	2.0298 mL	4.0596 mL	20.2980 mL
20 mM	0.2030 mL	1.0149 mL	2.0298 mL	10.1490 mL
50 mM	0.0812 mL	0.4060 mL	0.8119 mL	4.0596 mL
100 mM	0.0406 mL	0.2030 mL	0.4060 mL	2.0298 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc