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Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2 (Synonyms: RUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435...)

Catalog No. TMAC-00177 Copy Product Info
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Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB.

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAC-00177
Synonyms RUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435), p-RUNX1 (S435)

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB.

Anti-Phospho-RUNX1
(Ser435) Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB.
SynonymsRUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435), p-RUNX1 (S435)
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of extracts from 293 cells (Lane 2), HeLa cells (Lane 3) and HepG2 cells (Lane 4), using AML1 (Phospho-Ser435) Antibody TMAC-00177. The lane on the left is treated with antigen-specific peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of Serine 435( S-N-S(p)-P-T) derived from Human AML1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 53 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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