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Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2
(Synonyms: RUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435), p-RUNX1 (S435)) Copy Product Info
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Synonyms: RUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435), p-RUNX1 (S435)
Catalog No. TMAC-00177 Copy Product Info
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Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB.
Anti-Phospho-RUNX1
(Ser435) Polyclonal Antibody 2
(Ser435) Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB. |
| Synonyms | RUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435), p-RUNX1 (S435) |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 435( S-N-S(p)-P-T) derived from Human AML1 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 53 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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