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Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2

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Catalog No. TMAC-00177

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB.

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2

😃Good
Catalog No. TMAC-00177
Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2177-10 days
100 μL$3167-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of Serine 435( S-N-S(p)-P-T) derived from Human AML1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 53 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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