Shopping Cart
Remove All
Your shopping cart is currently empty
Ellipticine
Copy Product Info
🥰Excellent
Catalog No. T1166Cas No. 519-23-3
Alias NSC 71795, Elliptisine
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively.
Ellipticine
Copy Product Info🥰Excellent
Purity: 99.45%
Catalog No. T1166Alias NSC 71795, ElliptisineCas No. 519-23-3
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $47 | In Stock | In Stock | |
| 10 mg | $72 | In Stock | In Stock | |
| 25 mg | $119 | In Stock | In Stock | |
| 50 mg | $176 | In Stock | In Stock | |
| 100 mg | $262 | In Stock | In Stock | |
| 500 mg | $642 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $50 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:99.45%
Appearance:Solid
Color:Yellow
Contact us for more batch information
Product Introduction
Ellipticine AI Summary
Ellipticine exhibits significant cytotoxic and antiproliferative activity across a broad spectrum of human and animal cell lines, suggesting its potential as an anti-cancer agent. The compound has shown cytotoxicity with varying IC50 values depending on the cell type, with notable activities against human cancer cell lines such as A549 (lung cancer), Col2 (colon cancer), SNU-638 (stomach cancer), KB (epidermal carcinoma), and NCI-H187 (small cell lung cancer). In particular, it has demonstrated IC50 values ranging from 0.36 to 0.4 ug/mL against various cancer cell lines. Additionally, Ellipticine has exhibited pKa of 7.4, DNA binding bioactivity with a Log Kd of 5.18, and an increase in the denaturation temperature of calf thymus DNA by 9.8°C. Other significant activities include its effectiveness against murine leukemia L1210 cells both in vitro and in mice, enhancement of mean life span in treated mice, and inhibition of cellular protein synthesis in assays. Moreover, the compound has also shown activity against Plasmodium falciparum, indicating potential antiparasitic properties. Overall, Ellipticine demonstrates broad-spectrum cytotoxic effects and notable bioactivities, contributing to its attractiveness as a candidate for cancer and antiparasitic therapy..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively. |
| Targets&IC50 | MCF-7 cells:1.25±0.13μM, IMR-32 cells:0.27±0.02μM, UKF-NB-3 cells:0.44±0.03μM , UKF-NB-4 cells:0.49±0.04μM, HL-60 cells (leukemia):0.67±0.06μM, U-87MG cells (Glioblastoma):1.48±0.62 μM |
| Synonyms | NSC 71795, Elliptisine |
| Molecular Weight | 246.31 |
| Formula | C17H14N2 |
| Cas No. | 519-23-3 |
| Smiles | Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12 |
| Relative Density. | 1.257g/cm3 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 5 mg/mL (20.3 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Ellipticine | purchase Ellipticine | Ellipticine cost | order Ellipticine | Ellipticine chemical structure | Ellipticine formula | Ellipticine molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.