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MPP hydrochloride

Name: MPP hydrochloride
Brand: TargetMol
SKU: T21897L
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21897L

Alias MPP hydrochloride (289726-02-9 Free base)

MPP hydrochloride is a selective estrogen receptor (ERR) modulator.

MPP hydrochloride

🥰Excellent

Purity: 99.9%

Catalog No. T21897LAlias MPP hydrochloride (289726-02-9 Free base)

MPP hydrochloride is a selective estrogen receptor (ERR) modulator.

Pack Size	Price	Availability
1 mg	$45	In Stock
5 mg	$106	In Stock
10 mg	$172	In Stock
25 mg	$347	In Stock
50 mg	$587	In Stock
100 mg	$786	In Stock
200 mg	$1,080	In Stock
1 mL x 10 mM (in DMSO)	$118	In Stock

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Batch Information

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Purity:99.9%

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COA LCMS

Product Introduction

Bioactivity

Description	MPP hydrochloride is a selective estrogen receptor (ERR) modulator.
In vitro	MPP hydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines [1].
In vivo	MPP hydrochloride reverses the positive effects of beta-estradiol. MPP hydrochloride has mixed agonist/antagonist action on murine uterine ERalpha in vivo [1].
Synonyms	MPP hydrochloride (289726-02-9 Free base)

Chemical Properties

Molecular Weight	506.04
Formula	C₂₉H₃₂ClN₃O₃
Smiles	OC1=CC=C(C2=NN(C3=CC=C(O)C=C3)C(C4=CC=C(OCCN5CCCCC5)C=C4)=C2C)C=C1.Cl
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (108.69 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.95 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9761 mL	9.8806 mL	19.7613 mL	98.8064 mL
5 mM	0.3952 mL	1.9761 mL	3.9523 mL	19.7613 mL
10 mM	0.1976 mL	0.9881 mL	1.9761 mL	9.8806 mL
20 mM	0.0988 mL	0.4940 mL	0.9881 mL	4.9403 mL
50 mM	0.0395 mL	0.1976 mL	0.3952 mL	1.9761 mL
100 mM	0.0198 mL	0.0988 mL	0.1976 mL	0.9881 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc