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Anti-ALDH1A1 Antibody-PE (6M553)
🥰Excellent
Catalog No. TMAY-01851P
Anti-ALDH1A1 Antibody-PE (6M553) is a PE-conjugated Mouse antibody targeting ALDH1A1. Anti-ALDH1A1 Antibody-PE (6M553) can be used in FCM.
Anti-ALDH1A1 Antibody-PE (6M553)
Anti-ALDH1A1 Antibody-PE (6M553)
🥰Excellent
Catalog No. TMAY-01851P
Anti-ALDH1A1 Antibody-PE (6M553) is a PE-conjugated Mouse antibody targeting ALDH1A1. Anti-ALDH1A1 Antibody-PE (6M553) can be used in FCM.
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Chemical Properties
| Description | Anti-ALDH1A1 Antibody-PE (6M553) is a PE-conjugated Mouse antibody targeting ALDH1A1. Anti-ALDH1A1 Antibody-PE (6M553) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6M553 |
| Reactivity | Human |
| Verified Activity | Profile of anti-Human ALDH1A1 reactivity on A549 cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALDH1A1 / ALDH1 (rh ALDH1A1 / ALDH1; TMPY-01583; NP_000680.2; Ser2-Ser501) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea. Increased ALDH1A1 activity has been found in the stem cell populations of leukemia and some solid tumors. In tumor specimens, increased ALDH1A1 immunopositivity was found not only in secretory type cancer epithelial cells but also in neuroendocrine tumor populations. ALDH1 has been identified as a reliable marker of breast cancer stem cells. ALDH1 expression in primary cancer is an independent prognostic factor in node-positive breast cancer patients. ALDH1A1 plays a key role in normal hematopoiesis, and as a TLX1 transcriptional target, ALDH1A1 may contribute to the ability of this homeoprotein to alter cell fate and induce tumor growth. |
| Conjucates | PE |
| Others Formats | Unconjugated/FITC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human ALDH1A1 / ALDH1 protein (TMPY-01583) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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