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Anti-JAM-A Antibody-APC (5E755)

🥰Excellent
Catalog No. TMAY-00440A

Anti-JAM-A Antibody-APC (5E755) is a APC-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-APC (5E755) can be used in FCM.

Anti-JAM-A Antibody-APC (5E755)

Anti-JAM-A Antibody-APC (5E755)

🥰Excellent
Catalog No. TMAY-00440A
Anti-JAM-A Antibody-APC (5E755) is a APC-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-APC (5E755) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-JAM-A Antibody-APC (5E755) is a APC-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-APC (5E755) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
Clone
5E755
Reactivity
Human
Verified Activity
Profile of anti-JAM-A (CD321) reactivity on SKBR3 cells analyzed by flow cytometry.
Application
FCM
Recommended Dose
2 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAM-A / F11R / CD321 (rh JAM-A / F11R / CD321; TMPY-01035; NP_058642.1; Met 1-Ala 242) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundJunctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Human JAM-A / F11R / CD321 protein (TMPY-01035)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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