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Anti-SDCBP Antibody (8Z224)
(Synonyms: TACIP18, syndecan binding protein (syntenin), SYCL, ST1, MDA-9, MDA9) Copy Product Info
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Synonyms: TACIP18, syndecan binding protein (syntenin), SYCL, ST1, MDA-9, MDA9
Catalog No. TMAH-01077 Copy Product Info
🥰Excellent
Anti-SDCBP Antibody (8Z224) is an antibody targeting SDCBP. Anti-SDCBP Antibody (8Z224) can be used in ELISA,FCM,IF,WB.
Anti-SDCBP Antibody
(8Z224)
(8Z224)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SDCBP Antibody (8Z224) is an antibody targeting SDCBP. Anti-SDCBP Antibody (8Z224) can be used in ELISA,FCM,IF,WB. |
| Synonyms | TACIP18, syndecan binding protein (syntenin), SYCL, ST1, MDA-9, MDA9 |
| Ig Type | Rabbit IgG |
| Clone | 8Z224 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:2000; IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell junction, focal adhesion. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus. Melanosome. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Secreted, extracellular exosome. Membrane raft. |
| Tissue Specificity | Expressed in lung cancers, including adenocarcinoma, squamous cell carcinoma and small-cell carcinoma (at protein level). Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis. Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1. In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis. Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer types. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human SDCBP |
| Antigen Species | Human |
| Gene Name | SDCBP |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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