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Anti-IFN gamma Antibody-PerCP (9I367) is a PerCP-conjugated Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody-PerCP (9I367) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 T | $105 | 7-10 days | |
100 T | $329 | 7-10 days |
Description | Anti-IFN gamma Antibody-PerCP (9I367) is a PerCP-conjugated Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody-PerCP (9I367) can be used in FCM. |
Alias | interferon, γ, interferon, gamma, IFN γ |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9I367 |
Reactivity | Human |
Application | FCM |
Recommended Dose | 5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Interferon Gamma/IFN gamma/IFNG (rh Interferon Gamma/IFN gamma/IFNG; TMPY-01714; NP_000610.2; Met1-Gln166) and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | PerCP |
Others Formats | Unconjugated/APC/FITC/PE |
Antibody Types Available | 5 |
Immunogen | Recombinant Human Interferon Gamma/IFN gamma/IFNG Protein (TMPY-01714) |
Antigen Species | Human |
Biology Area | Neuroinflammation |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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