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Anti-CEL Antibody (3I694) is a Rabbit antibody targeting CEL. Anti-CEL Antibody (3I694) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Mouse |
Alias | carboxyl ester lipase, BAL, 1810036E18Rik |
Ig Type | Rabbit IgG |
Clone | 3I694 |
Reactivity | Mouse |
Verified Activity | Immunochemical staining of mouse CEL in mouse pancreas with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Bile salt-activated lipase / CEL (rM Bile salt-activated lipase / CEL; TMPY-03353; NP_034015.1; Met1-Leu534). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL cause maturity-onset diabetes of the young as well as pancreatic exocrine dysfunction. The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or -stimulated lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the duodenum. CEL is mainly expressed in pancreatic acinar cells and lactating mammary glands. The human CEL gene resides on chromosome 9q34.3 and contains a variable number of tandem repeats (VNTR) region that encodes a mucin-like protein tail. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Mouse Bile salt-activated lipase / CEL Protein (TMPY-03353) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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