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Synonyms: arginase 1, ARG1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $270 | 7-10 days | 7-10 days |
| Description | Anti-Arginase 1/ARG1 Antibody (5R257) is a Rabbit antibody targeting Arginase 1/ARG1. Anti-Arginase 1/ARG1 Antibody (5R257) can be used in ELISA,FCM,ICC/IF,IHC-P,WB. |
| Synonyms | arginase 1, ARG1 |
| Ig Type | Rabbit IgG |
| Clone | 5R257 |
| Reactivity | Human |
| Specificity | Human Arginase 1/ARG1 |
| Application | |
| Recommended Dose | WB: 1:500-1:1000; ELISA: 1:25000-1:50000; IHC-P: 1:500-1:2500; ICC-IF: 1:20-1:100; FCM: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ARG1 / Arginase 1 (rh ARG1 / Arginase 1; TMPY-02168; P05089-1; Met 1-Lys 322). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ARG1 / Arginase 1 protein (TMPY-02168) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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