AKR1C3 Protein, Human, Recombinant (His)

Name: AKR1C3 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00962
Rating: 4.5 (1 reviews)

(Synonyms: Dihydrodiol Dehydrogenase, Chlordecone Reductase Homolog HAKRb, Aldo-Keto Reductase Family 1 Member C3, 3-α-Hydroxysteroid Dehydrogenase Type 2, 3-α-HSD Type II Brain, 3-α-HSD Type 2, 3-Alpha-Hydroxysteroid Dehydrogenase Type 2, 3-Alpha-HSD Type II Brain, 3-Alpha-HSD Type 2, 17-β-Hydroxysteroid Dehydrogenase Type 5, 17-β-HSD 5, 17-Beta-Hydroxysteroid Dehydrogenase Type 5, 17-Beta-HSD 5) Copy Product Info

Synonyms: Dihydrodiol Dehydrogenase, Chlordecone Reductase Homolog HAKRb, Aldo-Keto Reductase Family 1 Member C3, 3-α-Hydroxysteroid Dehydrogenase Type 2, 3-α-HSD Type II Brain, 3-α-HSD Type 2, 3-Alpha-Hydroxysteroid Dehydrogenase Type 2, 3-Alpha-HSD Type II Brain, 3-Alpha-HSD Type 2, 17-β-Hydroxysteroid Dehydrogenase Type 5, 17-β-HSD 5, 17-Beta-Hydroxysteroid Dehydrogenase Type 5, 17-Beta-HSD 5

Catalog No. TMPJ-00962 Copy Product Info

Purity: 99%

AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.

AKR1C3 Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	7-10 days	7-10 days
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	P42330
Amino Acid	Met1-Tyr323
Construction	Met1-Tyr323
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 6% Sucrose, 2% Glycine, 100 mM NaCl, 0.05% Tween 80, pH 6.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Dihydrodiol Dehydrogenase, Chlordecone Reductase Homolog HAKRb, Aldo-Keto Reductase Family 1 Member C3, 3-α-Hydroxysteroid Dehydrogenase Type 2, 3-α-HSD Type II Brain, 3-α-HSD Type 2, 3-Alpha-Hydroxysteroid Dehydrogenase Type 2, 3-Alpha-HSD Type II Brain, 3-Alpha-HSD Type 2, 17-β-Hydroxysteroid Dehydrogenase Type 5, 17-β-HSD 5, 17-Beta-Hydroxysteroid Dehydrogenase Type 5, 17-Beta-HSD 5
Research Background	AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.

Chemical Properties

Molecular Weight

38 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.