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Anti-VEGFR2/KDR Polyclonal Antibody 2
😃Good
Catalog No. TMAB-01958
Anti-VEGFR2/KDR Polyclonal Antibody 2 is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Polyclonal Antibody 2 can be used in WB.
Anti-VEGFR2/KDR Polyclonal Antibody 2
Anti-VEGFR2/KDR Polyclonal Antibody 2
😃Good
Catalog No. TMAB-01958
Anti-VEGFR2/KDR Polyclonal Antibody 2 is a Rabbit antibody targeting VEGFR2/KDR. Anti-VEGFR2/KDR Polyclonal Antibody 2 can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Polyclonal Application: WB Reactivity: Human |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Sample: Lane 1: Recombinant human VEGFR2 protein, His (HEK293) Primary: Anti-VEGFR2 (TMAB-01958) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 147 kDa Observed band size: 147 kDa 2. Sample: Lane 1: Recombinant Human VEGFR2 Protein at 500ng Lane 2: Recombinant Human VEGFR2 Protein at 50ng Primary: Rabbit Anti-VEGFR-2 Polyclonal Antibody at 1/1000 dilution (Cat.TMAB-01958) Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 87 kDa Observed band size: 125-155 kD |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Nucleus. Cytoplasmic vesicle. Early endosome. Note=Detected on caveolae-enriched lipid rafts at the cell surface. Is recycled from the plasma membrane to endosomes and back again. Phosphorylation triggered by VEGFA binding promotes internalization and subsequent degradation. VEGFA binding triggers internalization and translocation to the nucleus. Isoform 2: Secreted (Probable).Isoform 3: Secreted. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]. |
| Immunogen | KLH conjugated synthetic peptide: human VEGFR2 |
| Antigen Species | Human |
| Gene ID | 3791 |
| Uniprot ID | |
| Biology Area | Response to hypoxia,VEGF,Angiogenic growth factors,Growth factor receptors,Endothelial Cell Markers,VEGF Receptors,Endothelial Cells,Hypoxia,Host Virus Interaction,VEGF,Receptor Tyrosine Kinases,Endothelial Markers,Surface Molecules |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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