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Anti-Neuropeptide Y Polyclonal Antibody (Synonyms: PYY4, neuropeptide Y)
Catalog No. TMAB-01221 Copy Product Info
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Anti-Neuropeptide Y Polyclonal Antibody is a Rabbit antibody targeting Neuropeptide Y. Anti-Neuropeptide Y Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
Anti-Neuropeptide Y Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01221
Synonyms PYY4, neuropeptide Y
Anti-Neuropeptide Y Polyclonal Antibody is a Rabbit antibody targeting Neuropeptide Y. Anti-Neuropeptide Y Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
Anti-Neuropeptide Y Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Neuropeptide Y Polyclonal Antibody is a Rabbit antibody targeting Neuropeptide Y. Anti-Neuropeptide Y Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P. |
| Synonyms | PYY4, neuropeptide Y |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Cow,Horse,Rabbit) |
| Verified Activity | 1. Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-NPY/Neuropeptide Y Polyclonal Antibody, Unconjugated (TMAB-01221) 1:400, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Paraformaldehyde-fixed, paraffin embedded (Rat adrenal gland); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Neuropeptide Y) Polyclonal Antibody, Unconjugated (TMAB-01221) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.   |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014] |
| Immunogen | KLH conjugated synthetic peptide: human NPY |
| Antigen Species | Human |
| Gene Name | NPY |
| Gene ID | |
| Protein Name | Pro-neuropeptide Y |
| Biology Area | Angiogenic Factors,Inotropics,Hypertrophy,Vasoconstriction,Metabolism,Hormones,More Neuropeptides |
| Function | NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. |
| Molecular Weight | Theoretical: 4/8 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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