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Anti-Neuropeptide Y Polyclonal Antibody is a Rabbit antibody targeting Neuropeptide Y. Anti-Neuropeptide Y Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-Neuropeptide Y Polyclonal Antibody is a Rabbit antibody targeting Neuropeptide Y. Anti-Neuropeptide Y Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
Alias | PYY4, neuropeptide Y |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat (predicted:Cow,Horse,Rabbit) |
Verified Activity | 1. Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-NPY/Neuropeptide Y Polyclonal Antibody, Unconjugated (TMAB-01221) 1:400, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Formalin-fixed and paraffin-embedded rat brain tissue labeled with Rabbit Anti-NPY/Neuropeptide Y Polyclonal Antibody, Unconjugated (TMAB-01221) at 1:400 followed byconjugation to the secondary antibody and DAb staining. 3. Paraformaldehyde-fixed, paraffin embedded (Rat adrenal gland); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Neuropeptide Y) Polyclonal Antibody, Unconjugated (TMAB-01221) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. |
Application | IHC-P,IHC-Fr,IF |
Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014] |
Immunogen | KLH conjugated synthetic peptide: human NPY |
Antigen Species | Human |
Gene ID | |
Biology Area | Angiogenic Factors,Inotropics,Hypertrophy,Vasoconstriction,Metabolism,Hormones,More Neuropeptides |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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