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Anti-MKP1 Polyclonal Antibody (Synonyms: VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, P...)
Catalog No. TMAB-01146 Copy Product Info
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Anti-MKP1 Polyclonal Antibody is a Rabbit antibody targeting MKP1. Anti-MKP1 Polyclonal Antibody can be used in WB.
Anti-MKP1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01146
Synonyms VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, PTPN10, PTPN 10, Protein tyrosine phosphatase CL100, Mkp1, MKP 1, Mitogen activated protein kinase phosphatase 1, MAP kinase phosphatase 1, HVH1, HVH 1, EC 3.1.3.48, EC 3.1.3.16, DUSP-1, DUSP1, Dual specificity protein phosphatase hVH1, Dual specificity protein phosphatase 1, Dual Specificity Phosphatase 1, CL100, CL 100, 3ch134
Anti-MKP1 Polyclonal Antibody is a Rabbit antibody targeting MKP1. Anti-MKP1 Polyclonal Antibody can be used in WB.
Anti-MKP1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
Antigen Details
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| Description | Anti-MKP1 Polyclonal Antibody is a Rabbit antibody targeting MKP1. Anti-MKP1 Polyclonal Antibody can be used in WB. |
| Synonyms | VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, PTPN10, PTPN 10, Protein tyrosine phosphatase CL100, Mkp1, MKP 1, Mitogen activated protein kinase phosphatase 1, MAP kinase phosphatase 1, HVH1, HVH 1, EC 3.1.3.48, EC 3.1.3.16, DUSP-1, DUSP1, Dual specificity protein phosphatase hVH1, Dual specificity protein phosphatase 1, Dual Specificity Phosphatase 1, CL100, CL 100, 3ch134 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: Lane 1: Human HeLa cell lysates Lane 2: Human HUVEC cell lysates Primary: Anti-MKP1 (TMAB-01146) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 39 kDa Observed band size: 39 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. |
| Immunogen | KLH conjugated synthetic peptide: human DUSP1 |
| Antigen Species | Human |
| Gene Name | DUSP1 |
| Gene ID | |
| Protein Name | Dual specificity protein phosphatase 1 |
| Uniprot ID | |
| Biology Area | Ser / Thr Phosphatases,Tyrosine Phosphatases |
| Function | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185'. |
| Molecular Weight | Theoretical: 39 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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