SCF Protein, Rat, Recombinant (HEK293, His)

Name: SCF Protein, Rat, Recombinant (HEK293, His)
Brand: TargetMol
SKU: TMPJ-00895
Rating: 4.5 (1 reviews)

(Synonyms: steel factor, SLF, SFc-Kit ligand, SCFStem cell factor, SCF, MGFSHEP7, MGF, Mast cell growth factor, KL-1, KITLG, Kitl, KIT ligand, FPH2) Copy Product Info

Synonyms: steel factor, SLF, SFc-Kit ligand, SCFStem cell factor, SCF, MGFSHEP7, MGF, Mast cell growth factor, KL-1, KITLG, Kitl, KIT ligand, FPH2

Catalog No. TMPJ-00895 Copy Product Info

SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.

SCF Protein, Rat, Recombinant (HEK293, His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	7-10 days	7-10 days
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.
Species	Rat
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	P21581
Amino Acid	Gln26-Ala189
Construction	Gln26-Ala189
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	steel factor, SLF, SFc-Kit ligand, SCFStem cell factor, SCF, MGFSHEP7, MGF, Mast cell growth factor, KL-1, KITLG, Kitl, KIT ligand, FPH2
Research Background	SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.

Chemical Properties

Molecular Weight

23-40 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.