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TargetMol | Compound Library

Anti-Cancer Active Compound Library

Catalog No. L2160

During the past decades, we have witnessed many landmark discoveries and successes in cancer research and therapy, however, cancer is still a major health problem for human beings, and it often physically and emotionally brings pains and difficulties to those living with it. Cancer cells remain undifferentiated (continue to divide, causing more damage, and invading new tissue), lack normal cell signaling responses (loss of contact inhibition and evasion of programmed cell death), contain abnormal changes (genetic abnormalities) in chromatin, have altered energy metabolism, and induce vascularization (ensure a steady supply of oxygen and nutrients).

We carefully select 4270 compounds with known anti-tumor activity as Anticancer Active Compound Library that can be used for tumor-related research and anti-tumor drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2160

Anti-Cancer Active Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 4270 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for molecular mechanism of tumorigenesis, and anti-tumor drug screening;
  • Covers various major targets including PI3K, HDAC, mTOR, CDK, Aurora Kinase, JAK, etc.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
Antibacterial
Endogenous Metabolite
DNA/RNA Synthesis
NF-κB
CDK
PI3K
EGFR
ROS
Ras
VEGFR
Akt
Antibiotic
Parasite
Microtubule Associated
mTOR
Topoisomerase
Epigenetic Reader Domain
Caspase
Antifungal
Reactive Oxygen Species
Bcl-2 Family
ERK
FLT
Nucleoside Antimetabolite/Analog
Dehydrogenase
STAT
PDGFR
PARP
HDAC
COX
Histone Methyltransferase
p38 MAPK
FGFR
c-Met/HGFR
TNF
Estrogen Receptor/ERR
Wnt/beta-catenin
HIV Protease
Cytochromes P450
c-Kit
Ferroptosis
MDM-2/p53
Src
JAK
Interleukin
Raf
Phosphatase
HSP
MMP
Antioxidant
Virus Protease
Influenza Virus
Estrogen/progestogen Receptor
KRas
PKC
Bcr-Abl
NO Synthase
ALK
AMPK
Aurora Kinase
Androgen Receptor
PPAR
BTK
Nrf2
E1/E2/E3 Enzyme
JNK
Calcium Channel
P-gp
SARS-CoV
MEK
FAK
DUB
HIF/HIF Prolyl-Hydroxylase
GSK-3
IL Receptor
TLR
MAPK
PROTACs
p53
HSV
IGF-1R
Mitophagy
TGF-beta/Smad
AChR
Antiviral
Drug Metabolite
Mitochondrial Metabolism
DNA Alkylator/Crosslinker
c-RET
Chk
PDE
Histone Demethylase
Lipoxygenase
Sirtuin
ATM/ATR
Gamma-secretase
Potassium Channel
TAM Receptor
Tyrosine Kinases
HER
Trk receptor
c-Fms
Histone Acetyltransferase
Sodium Channel
Cholinesterase (ChE)
DNA-PK
Pim
Adrenergic Receptor
Molecular Glues
Mdm2
Retinoid Receptor
PERK
Casein Kinase
Proteasome
5-HT Receptor
S6 Kinase
HIF
ROS Kinase
Reductase
Hedgehog/Smoothened
Transferase
PLK
GABA Receptor
PD-1/PD-L1
Integrin
Smo
DNA Methyltransferase
ADC Cytotoxin
Kinesin
Serine Protease
IAP
Anti-infection
Aryl Hydrocarbon Receptor
CXCR
HBV
Histamine Receptor
YAP
Fatty Acid Synthase
HCV Protease
Glutathione Peroxidase
Tyrosinase
PKA
DNA Alkylation
TRP/TRPV Channel
LPL Receptor
Antifolate
c-Myc
Phospholipase
Beta Amyloid
PDK
Dopamine Receptor
Antifection
Ligands for E3 Ligase
Indoleamine 2,3-Dioxygenase (IDO)
S1P Receptor
Isocitrate Dehydrogenase (IDH)
IDO
GPCR
Serine/threonin kinase
DNA
IκB/IKK
transporter
MAO
Aromatase
Prostaglandin Receptor
Carbonic Anhydrase
DHFR
CSF-1R
IKZF
Immunology/Inflammation related
Syk
Adenosine Receptor
DYRK
Rho
NOS
OXPHOS
ATPase
ROCK
CaMK
Monoamine Oxidase
Glutaminase
Survivin
Cell Cycle Arrest
Monocarboxylate transporter
glycosidase
NADPH
AhR
RIP kinase
BCRP
Progesterone Receptor
Photosensitizer
Ephrin Receptor
Reverse Transcriptase
NOD
Cysteine Protease
STING
Glucosidase
IFNAR
Telomerase
Wee1
Methionine Adenosyltransferase (MAT)
Amino Acids and Derivatives
MNK
GNRH Receptor
PAK
PAI-1
IRAK
Proton pump
Opioid Receptor
GPX
iGluR
CCR
Tie-2
Cholecystokinin Receptor
Acyltransferase
RANKL/RANK
Glucocorticoid Receptor
NOD-like Receptor (NLR)
P2X Receptor
Somatostatin
Discoidin Domain Receptor (DDR)
MicroRNA
NAMPT
Chloride channel
IRE1
ABC Transporter
RAAS
Bcl-6
PYK2
UGT
Aminopeptidase
HMG-CoA Reductase
p97
ROR
Ligands for Target Protein for PROTAC
Glucokinase
Angiotensin-converting Enzyme (ACE)
Orphan Receptor
Liver X Receptor
Leukotriene Receptor
Pyroptosis
Cannabinoid Receptor
PKM
ATG
GluR
Endothelin Receptor
Necroptosis
Lipid
PSMA
LPA Receptor
BMI-1
Thrombin
DAPK
Galectin
MTH1
NMDAR
Hexokinase
Complement System
GTPase
cAMP
MELK
GST
MALT
PTEN
FAAH
p62
Hydroxylase
Myosin
Neurokinin receptor
FOXO
CRM1
MRP
PAD
ASK
Protease-activated Receptor
Lipase
PANoptosis
Protease
KLF
Factor Xa
Platelet aggregation
MyD88
Arrestin
FXR
Xanthine Oxidase
KSP
Cadherin
MLK
NEDD8
LTR
NR4A
Porcupine
CD73
ribosome
CRISPR/Cas9
TOPK
Serotonin Transporter
Decarboxylase
Adenosine Deaminase
APC/C
GRK
Bombesin Receptor
ACK1
SGK
MIF
Neurotensin Receptor
Adenylate cyclase
Thrombopoietin Receptor
Cuproptosis
PAFR
Haspin Kinase
GPCR19
RSV
Drug-Linker Conjugates for ADC
PI4K
CaSR
Gap Junction Protein
Lysosomal Autophagy
RAR/RXR
DNA gyrase
Acetyl-CoA Carboxylase
FKBP
Factor VIIa
Vitamin
Adiponectin Receptor
ATP Citrate Lyase
E3 Ligase Ligand-Linker Conjugates
Hippo pathway
Sigma receptor
CFTR
Thyroid hormone receptor(THR)
FLAP
Beta-Secretase
Hck
Annexin A
Arp2/3 Complex
Stearoyl-CoA Desaturase (SCD)
HuR
FOXO3
PARG(Poly(ADP-ribose) Glycohydrolase)
GlyT
PGE Synthase
Urea Transporter
Aquaporin
Apelin receptor
CYP19A1
Dynamin
P2Y Receptor
B7
DPP-4
HCAR
NEDD4-1
Tight Junction Protein
CAT
Y Box Binding Protein 1
Arginase
Na+/Ca2+ Exchanger
gp120/CD4
Vasopressin Receptor
Carboxypeptidase
Melanocortin Receptor
Dipeptidyl Peptidase
Oxytocin Receptor
GHSR
Melatonin Receptor
Amylase
Prolyl Endopeptidase (PREP)
FABP
LDL
Epoxide Hydrolase
LRRK2
Free radical scavengers
GluCls
RXFP receptor
NADPH-oxidase
Glyoxalase
CD38
VDA
Target Protein Ligand-Linker Conjugates
LAG-3
PROTAC Linker
Transketolase
NPC1L1
Kisspeptin
LDLR
SIK
Thioredoxin
Glutathione reductase
Liposome
Advanced Glycation End Products
NUDIX hydrolase
BACE
OCT
Stemness kinase
Na-K-Cl cotransporter
Neuropeptide Y Receptor
SGLT
TMV
Ferroportin
ADC Linker
Poly(ADP-ribose) Glycohydrolase (PARG)

Keywords