Granzyme B/GZMB Protein, Mouse, Recombinant (His)

Name: Granzyme B/GZMB Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00770
Price: 112 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: H), Gzmb, Granzyme B(G, Fragmentin-2, Cytotoxic cell protease 1, CTLA-1, Ctla1, CCP1) Copy Product Info

Synonyms: H), Gzmb, Granzyme B(G, Fragmentin-2, Cytotoxic cell protease 1, CTLA-1, Ctla1, CCP1

Catalog No. TMPJ-00770 Copy Product Info

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Granzyme B/GZMB Protein, Mouse, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	-	In Stock
10 µg	$183	-	In Stock
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Liquid

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	P04187
Amino Acid	Gly19-Ser247
Construction	Gly19-Ser247
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Synonyms	H), Gzmb, Granzyme B(G, Fragmentin-2, Cytotoxic cell protease 1, CTLA-1, Ctla1, CCP1
Research Background	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Chemical Properties

Molecular Weight

35 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Dose Conversion

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Tech Support

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Keywords

CTLA 1CCP-1CCP 1

Related Tags: Granzyme B/GZMB Protein, Mouse, Recombinant (His) chemical structure | Granzyme B/GZMB Protein, Mouse, Recombinant (His) molecular weight