Granzyme B/GZMB Protein, Mouse, Recombinant (His)

Catalog No. TMPJ-00770 Copy Product Info

Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Granzyme B/GZMB Protein, Mouse, Recombinant (His)

Catalog No. TMPJ-00770

Copy Product Info

Granzyme B/GZMB Protein, Mouse, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$112	7-10 days	7-10 days
10 μg	$183	7-10 days	7-10 days
20 μg	$292	7-10 days	7-10 days
50 μg	$545	7-10 days	7-10 days
100 μg	$792	7-10 days	7-10 days
200 μg	$1,150	7-10 days	7-10 days
500 μg	$1,900	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

Add to Cart

Add to Quotation

For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	P04187
Synonyms	H),Gzmb,Granzyme B(G,Fragmentin-2,Cytotoxic cell protease 1,CTLA-1,Ctla1,CCP1
Amino Acid	Gly19-Ser247
Construction	Gly19-Ser247
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	35 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.