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IL-15 Protein, Mouse, Recombinant

(Synonyms: IL-15, Il15) Copy Product Info

Synonyms: IL-15, Il15

Catalog No. TMPY-07190 Copy Product Info
IL-15 Protein, Mouse, Recombinant is expressed in HEK293 Cells. The accession number is P48346-1.
IL-15 Protein, Mouse, Recombinant
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$98-In Stock
10 μg$163-In Stock
20 μg$2727-10 days7-10 days
50 μg$539-In Stock
100 μg$8497-10 days7-10 days
200 μg$1,3307-10 days7-10 days
500 μg$2,4807-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:≥ 90 % as determined by SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Immobilized Recombinant Mouse IL-15 Protein at 2 μg/mL (100 μL/well) can bind Recombinant Mouse IL15RA Protein (ECD, Fc Tag), the EC50 is 300-1200 ng/mL (QC tested).
Description
IL-15 Protein, Mouse, Recombinant is expressed in HEK293 Cells. The accession number is P48346-1.
Species
Mouse
Expression System
HEK293 Cells
TagTag Free
Accession NumberP48346-1
ConstructionA DNA sequence encoding the Mouse IL15 (P48346-1) (Asn49-Ser162) was expressed with two amino acids (GP) at the N-terminus.
Protein Purity
≥ 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from sterile PBS, 10% trehalose, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
ReconstitutionReconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsIL-15, Il15
Research Background
The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietic receptor subunits and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively, spliced transcript variants of this gene have been reported.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Chemical Properties
Molecular Weight13.41 kDa (predicted); 26.7 kDa and 23.5 kDa (reducing contition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: IL-15 Protein, Mouse, Recombinant chemical structure | IL-15 Protein, Mouse, Recombinant molecular weight