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Anti-Phospho-PRKAA2 (Ser491) Antibody (6G961) is an antibody targeting Phospho-PRKAA2 (Ser491). Anti-Phospho-PRKAA2 (Ser491) Antibody (6G961) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $207 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Anti-Phospho-PRKAA2 (Ser491) Antibody (6G961) is an antibody targeting Phospho-PRKAA2 (Ser491). Anti-Phospho-PRKAA2 (Ser491) Antibody (6G961) can be used in ELISA, WB. |
Alias | Protein kinase AMP activated catalytic subunit alpha 2, Protein kinase AMP activated alpha 2 catalytic subunit, PRKAA 2, PRKAA, Phospho-PRKAA2 (S491), Hydroxymethylglutaryl CoA reductase kinase, HMGCR kinase, AMPKalpha2, AMPKa2, AMPK2, AMPK subunit alpha-2, AMPK alpha 2 chain, Acetyl-CoA carboxylase kinase, ACACA kinase, AAPK2_HUMAN, 5'-AMP-activated protein kinase catalytic subunit alpha-2 |
Ig Type | Rabbit IgG |
Clone | 6G961 |
Reactivity | Human |
Verified Activity | Western Blot -Positive WB detected in 293 whole cell lysate, A549 whole cell lysate -All lanes Phospho-PRKAA2 antibody at 1.1μg/ml -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 62 KDa -Observed band size: 62 KDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:5000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cytoplasm. Nucleus. Note=In response to stress, recruited by p53/TP53 to specific promoters. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the a... |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human Phospho-PRKAA2 (S491) |
Antigen Species | Human |
Gene ID | 5563 |
Uniprot ID | |
Biology Area | Signal Transduction |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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