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MrgprX2 antagonist-8

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Catalog No. T63812Cas No. 2768216-96-0

MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases.

MrgprX2 antagonist-8

MrgprX2 antagonist-8

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Purity: 98.61%
Catalog No. T63812Cas No. 2768216-96-0
MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$106In StockIn Stock
5 mg$263In StockIn Stock
10 mg$378In StockIn Stock
25 mg$619In StockIn Stock
50 mg$818In StockIn Stock
100 mg$1,090-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.61%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases.
Chemical Properties
Molecular Weight540.99
FormulaC24H24ClF3N4O3S
Cas No.2768216-96-0
SmilesCS(=O)(=O)Nc1cccc(c1)C(=O)N[C@H]1CC[C@H](CC1)Nc1cc(nc2ccc(Cl)cc12)C(F)(F)F
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 225 mg/mL (415.9 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8485 mL9.2423 mL18.4846 mL92.4232 mL
5 mM0.3697 mL1.8485 mL3.6969 mL18.4846 mL
10 mM0.1848 mL0.9242 mL1.8485 mL9.2423 mL
20 mM0.0924 mL0.4621 mL0.9242 mL4.6212 mL
50 mM0.0370 mL0.1848 mL0.3697 mL1.8485 mL
100 mM0.0185 mL0.0924 mL0.1848 mL0.9242 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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