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Anti-CD166/ALCAM Antibody-APC (5S364)
🥰Excellent
Catalog No. TMAY-03021A
Anti-CD166/ALCAM Antibody-APC (5S364) is a APC-conjugated Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-APC (5S364) can be used in FCM.
Anti-CD166/ALCAM Antibody-APC (5S364)
Anti-CD166/ALCAM Antibody-APC (5S364)
🥰Excellent
Catalog No. TMAY-03021A
Anti-CD166/ALCAM Antibody-APC (5S364) is a APC-conjugated Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-APC (5S364) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD166/ALCAM Antibody-APC (5S364) is a APC-conjugated Rabbit antibody targeting CD166/ALCAM. Anti-CD166/ALCAM Antibody-APC (5S364) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 5S364 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse ALCAM(CD166) expression on mouse splenocytes. BABL/c splenocytes were stained with APC-conjugated anti-Mouse ALCAM(CD166). The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD166 / ALCAM (rM CD166 / ALCAM; TMPY-01153; NP_033785.1; Met1-Lys527) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Mouse CD166 / ALCAM protein (TMPY-01153) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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