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(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate comprising an E3 ligase ligand-linker and a VH032-based VHL ligand, commonly used in PROTAC technology. This compound is essential in synthesizing various PROTACs, such as UNC6852, a bivalent chemical degrader that specifically targets EED [1].

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|---|---|---|---|
| 100 mg | Inquiry | Backorder | |
| 500 mg | Inquiry | Backorder | 
| Description | (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate comprising an E3 ligase ligand-linker and a VH032-based VHL ligand, commonly used in PROTAC technology. This compound is essential in synthesizing various PROTACs, such as UNC6852, a bivalent chemical degrader that specifically targets EED [1].  | 
| In vitro | PROTACs comprise two distinct ligands joined by a linker: one targets an E3 ubiquitin ligase and the other binds to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [PROTACs]  | 
| Synonyms | VH032-C3-NH2 | 
| Molecular Weight | 515.67 | 
| Formula | C26H37N5O4S | 
| Cas No. | 2361119-88-0 | 
| Relative Density. | 1.242 g/cm3 (Predicted) | 
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | 

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