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Anti-PTH Antibody (4P622)

😃Good
Catalog No. TMAY-02529
Alias PTH1, PTH, parathyroid hormone

Anti-PTH Antibody (4P622) is a Mouse antibody targeting PTH. Anti-PTH Antibody (4P622) can be used in ELISA.

Anti-PTH Antibody (4P622)

Anti-PTH Antibody (4P622)

😃Good
Catalog No. TMAY-02529Alias PTH1, PTH, parathyroid hormone
Anti-PTH Antibody (4P622) is a Mouse antibody targeting PTH. Anti-PTH Antibody (4P622) can be used in ELISA.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-PTH Antibody (4P622) is a Mouse antibody targeting PTH. Anti-PTH Antibody (4P622) can be used in ELISA.
AliasPTH1, PTH, parathyroid hormone
Ig Type
Monoclonal Mouse IgG2b
Clone
4P622
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PTH / parathyroid hormone (rh PTH / parathyroid hormone; TMPY-02764; P01270; Ser32-Phe65). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundParathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide. PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Parathyroid hormone (PTH) has been proved to play a pivotal role in maintaining myocardial contractility as well as effective natriuresis, and possible pathogenic mechanisms contributing to heart failure secondary to hypocalcemia and hypoparathyroidism. With the increased population of preosteoblastic lineages and the osteoblastic activation, Parathyroid hormone (PTH) drives anabolism in bone. Experiments have recently reported that PTH affects bone cells in a dual pathway - mediating osteoblastic (preosteoblastic) activities or osteocytic synthesis of sclerostin. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human PTH / parathyroid hormone protein (TMPY-02764)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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