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1a,1b-dihomo Prostaglandin E2

Name: 1a,1b-dihomo Prostaglandin E2
Brand: TargetMol
SKU: T36045
Rating: 4.5 (1 reviews)

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Catalog No. T36045Cas No. 26198-80-1

Alias 1a,1b-dihomo Prostaglandin E2

1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid initially identified in sheep vesicular gland microsome extracts containing COX and incubated with adrenic acid. It has also been detected in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid. This compound is believed to be produced by the elongation of AA to adrenic acid, followed by sequential metabolism by COX and PGE synthase.

1a,1b-dihomo Prostaglandin E2

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Catalog No. T36045Alias 1a,1b-dihomo Prostaglandin E2Cas No. 26198-80-1

Pack Size	Price	USA Warehouse	Global Warehouse
500 μg	$429	35 days	35 days
1 mg	$790	35 days	35 days
5 mg	$3,500	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description

Synonyms

1a,1b-dihomo Prostaglandin E2

Chemical Properties

Molecular Weight	380.52
Formula	C₂₂H₃₆O₅
Cas No.	26198-80-1
Smiles	C(/C=C\CCCCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)CC1=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (262.8 mM), Sonication is recommended.

Ethanol: 100 mg/mL (262.8 mM), Sonication is recommended.

PBS (pH 7.2): 5 mg/mL (13.14 mM), Sonication is recommended.

DMF: 100 mg/mL (262.8 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	2.6280 mL	13.1399 mL	26.2798 mL	131.3991 mL
5 mM	0.5256 mL	2.6280 mL	5.2560 mL	26.2798 mL
10 mM	0.2628 mL	1.3140 mL	2.6280 mL	13.1399 mL

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
20 mM	0.1314 mL	0.6570 mL	1.3140 mL	6.5700 mL
50 mM	0.0526 mL	0.2628 mL	0.5256 mL	2.6280 mL
100 mM	0.0263 mL	0.1314 mL	0.2628 mL	1.3140 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc