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BiCAPPA

Name: BiCAPPA
Brand: TargetMol
SKU: T73416
Rating: 4.5 (1 reviews)

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Catalog No. T73416 Copy Product Info

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BiCAPPA is a bivalent anti-prion ligand. BiCAPPA reduces the levels of the infectious conformation of prion protein (PrPSc) in cells infected with yaws, with an EC50 value of 0.32 μM.

Cas No. 119662-55-4

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Pack Size	Price	USA Stock	Global Stock
1 mg	$88	Inquiry	Inquiry
5 mg	$213	Inquiry	Inquiry
10 mg	$347	Inquiry	Inquiry
25 mg	$695	Inquiry	Inquiry
50 mg	$1,090	Inquiry	Inquiry

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description

BiCAPPA is a bivalent anti-prion ligand. BiCAPPA reduces the levels of the infectious conformation of prion protein (PrPSc) in cells infected with yaws, with an EC50 value of 0.32 μM.

Chemical Properties

Molecular Weight	683.67
Formula	C₃₈H₄₀Cl₂N₆O₂
Cas No.	119662-55-4
Smiles	ClC=1C=CC=2C(=NC=3C=CC(OC)=CC3C2NCCCN4CCN(CC4)CCCNC5=C6C=CC(Cl)=CC6=NC=7C=CC(OC)=CC75)C1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 7.62 mg/mL (11.15 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4627 mL	7.3135 mL	14.6269 mL	73.1347 mL
5 mM	0.2925 mL	1.4627 mL	2.9254 mL	14.6269 mL
10 mM	0.1463 mL	0.7313 mL	1.4627 mL	7.3135 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Related Tags: BiCAPPA chemical structure | BiCAPPA formula | BiCAPPA molecular weight