Utibapril

Name: Utibapril
Brand: TargetMol
SKU: T13274
Rating: 4.5 (1 reviews)

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Catalog No. T13274Cas No. 109683-61-6

Alias FPL 63547

Utibapril, an inhibitor of angiotensin-converting enzyme (ACE), exhibits antihypertensive activities.

Utibapril

😃Good

Catalog No. T13274Alias FPL 63547Cas No. 109683-61-6

Utibapril, an inhibitor of angiotensin-converting enzyme (ACE), exhibits antihypertensive activities.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Utibapril, an inhibitor of angiotensin-converting enzyme (ACE), exhibits antihypertensive activities.
In vivo	Utibapril significantly inhibits plasma, renal, and vascular ACE but not ventricular ACE activity. Vascular ACE activity is significantly inhibited by Utibapril (2 μg/kg/day), and Utibapril (250 μg/kg/day) results in significant inhibition of plasma ACE. Additionally, angiotensin I-induced decreases in coronary flow in the isolated heart are significantly inhibited after treatment with higher doses of Utibapril [1]. FPL 63547 is rapidly and extensively excreted as the diacid in bile but appears in urine in negligible amounts [2].
Synonyms	FPL 63547

Chemical Properties

Molecular Weight	449.56
Formula	C₂₂H₃₁N₃O₅S
Cas No.	109683-61-6
Smiles	C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)SC(C(C)(C)C)=N2
Relative Density.	1.24g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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