Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) (Synonyms: PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt))

Catalog No. T37028 Copy Product Info
🥰Excellent
The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

Copy Product Info
🥰Excellent
Catalog No. T37028
Synonyms PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Cas No. 1628353-02-5
TargetMol | Customer service
Customer service consultation
Pack SizePriceUSA StockGlobal StockQuantity
100 μg$16835 days35 days
500 μg$74635 days35 days
1 mg$1,27035 days35 days
5 mg$5,68035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Resource Download

Product Introduction

Bioactivity
Description
The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.
SynonymsPtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Chemical Properties
Molecular Weight1138.9
FormulaC41H78Na4O22P4
Cas No.1628353-02-5
Smiles[Na].[Na].[Na].[Na].CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)O[C@@H]1[C@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCCjcExt:v:0:0,1:0,2:0,3:0
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
CHCl3:CH3OH:H2O (2.5:3:1): 3.8 mg/mL (3.34 mM), Sonication is recommended.
PBS (pH 7.2): 10 mg/mL (8.78 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)
1mg5mg10mg50mg
5 mM0.1756 mL0.8780 mL1.7561 mL8.7804 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PtdIns-(3,4,5)-P-3 (1,2-dipalmitoyl) (sodium salt)PtdIns(3,4,5)P3 (1,2dipalmitoyl) (sodium salt)PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)PtdIns (3,4,5) P3 (1,2 dipalmitoyl) (sodium salt)
Related Tags: buy PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) | purchase PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) cost | order PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) chemical structure | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) formula | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.