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Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody
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Catalog No. TMAC-03323
Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Tyr658). Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody can be used in WB.
Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody
Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody
😃Good
Catalog No. TMAC-03323
Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Tyr658). Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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| Description | Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Tyr658). Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP. Involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating and activating RAF1, which mediates the activation of the MAPK/ERK signaling cascade, and/or by up-regulating CDKN1A, which facilitates active cyclin-dependent kinase (CDK) complex formation in glioma cells. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 658(F-S-Y(p)-V-N) derived from Human PKC α |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 80 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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