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TOPBioactivityRelated Conjugates and FormulationsAntigen DetailsChemical infoStorage&SolubilityCalculator

Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody

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Catalog No. TMAC-03323
Alias Protein kinase C zeta, Protein kinase C gamma, Protein kinase C epsilon, Protein kinase C delta, Protein kinase C beta, Protein kinase C alpha, Protein kinase C, PRKCZ, PRKCG, PRKCE, PRKCD, PRKCB2, PRKCB1, PRKCB, PRKCA (p-Y658), PRKCA (p-Tyr658), PRKCA, p-PRKCA (Y658), p-PRKCA (Tyr658), PKCG, PKCE, PKCD, PKCB, PKC-alpha, PKC-A, PKCA, PKC2, PKC zeta, PKC gamma, PKC epsilon, PKC delta, PKC beta, PKC alpha, Phospho-PRKCA (Y658), KPCA_HUMAN

Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Tyr658). Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody can be used in WB.

Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody

Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody

😃Good
Catalog No. TMAC-03323Alias Protein kinase C zeta, Protein kinase C gamma, Protein kinase C epsilon, Protein kinase C delta, Protein kinase C beta, Protein kinase C alpha, Protein kinase C, PRKCZ, PRKCG, PRKCE, PRKCD, PRKCB2, PRKCB1, PRKCB, PRKCA (p-Y658), PRKCA (p-Tyr658), PRKCA, p-PRKCA (Y658), p-PRKCA (Tyr658), PKCG, PKCE, PKCD, PKCB, PKC-alpha, PKC-A, PKCA, PKC2, PKC zeta, PKC gamma, PKC epsilon, PKC delta, PKC beta, PKC alpha, Phospho-PRKCA (Y658), KPCA_HUMAN
Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Tyr658). Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3167-10 days
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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity
Description
Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKCA (Tyr658). Anti-Phospho-PRKCA (Tyr658) Polyclonal Antibody can be used in WB.
SynonymsProtein kinase C zeta, Protein kinase C gamma, Protein kinase C epsilon, Protein kinase C delta, Protein kinase C beta, Protein kinase C alpha, Protein kinase C, PRKCZ, PRKCG, PRKCE, PRKCD, PRKCB2, PRKCB1, PRKCB, PRKCA (p-Y658), PRKCA (p-Tyr658), PRKCA, p-PRKCA (Y658), p-PRKCA (Tyr658), PKCG, PKCE, PKCD, PKCB, PKC-alpha, PKC-A, PKCA, PKC2, PKC zeta, PKC gamma, PKC epsilon, PKC delta, PKC beta, PKC alpha, Phospho-PRKCA (Y658), KPCA_HUMAN
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of extracts from COLO205 cells using PKC α (Phospho-Tyr658) Antibody TMAC-03323. The lane on the right is treated with the antigen-specific peptide.
Application
WB
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCalcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP. Involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating and activating RAF1, which mediates the activation of the MAPK/ERK signaling cascade, and/or by up-regulating CDKN1A, which facilitates active cyclin-dependent kinase (CDK) complex formation in glioma cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 658(F-S-Y(p)-V-N) derived from Human PKC α
Antigen Species
human
Uniprot ID
P17252
Chemical Properties
Molecular WeightActual: 80 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PRKCA (pY658)PRKCA (pTyr658)PRKCA (phospho-Y658)PRKCA (phospho-Tyr658)pPRKCA (Y658)pPRKCA (Tyr658)
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