MASP2 Protein, Rat, Recombinant (E. coli, His)

Name: MASP2 Protein, Rat, Recombinant (E. coli, His)
Brand: TargetMol
SKU: TMPK-00581
Rating: 4.5 (1 reviews)

(Synonyms: sMap, MASP-2, MASP1P1, MAP19) Copy Product Info

Synonyms: sMap, MASP-2, MASP1P1, MAP19

Catalog No. TMPK-00581 Copy Product Info

MASP2 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.

Pack Size	Price	USA Stock	Global Stock
10 µg	$116	7-10 days	7-10 days
20 µg	$188	7-10 days	7-10 days
50 µg	$373	7-10 days	7-10 days
100 µg	$627	-	In Stock
200 µg	$1,130	7-10 days	7-10 days
500 µg	$2,510	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Tris-Bis PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Rat MASP2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-MASP2 Antibody, hFc Tag with the EC50 of 8.9ng/ml determined by ELISA.
Description	MASP2 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
Species	Rat
Expression System	E. coli
Tag	C-His
Accession Number	A2VCV7
Construction	Thr287-Phe685
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 50 mM Tris, 200 mM NaCl (pH 9.0).
Synonyms	sMap, MASP-2, MASP1P1, MAP19
Research Background	The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.

Chemical Properties

Molecular Weight

46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.