ULBP-4 Protein, Human, Recombinant (hFc)

Name: ULBP-4 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-00193
Rating: 4.5 (1 reviews)

(Synonyms: ULBP4, RL-4, retinoic acid early transcript 1E, RAET1E2, NKG2DL4, N2DL-4, LETAL, bA350J20.7) Copy Product Info

Synonyms: ULBP4, RL-4, retinoic acid early transcript 1E, RAET1E2, NKG2DL4, N2DL-4, LETAL, bA350J20.7

Catalog No. TMPY-00193 Copy Product Info

The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.12 kDa and the accession number is Q8TD07-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$108	7-10 days	7-10 days
20 µg	$178	7-10 days	7-10 days
50 µg	$359	7-10 days	7-10 days
100 µg	$696	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Human ULBP-4, hFc Tag captured on CM5 Chip via Protein A can bind Human NKG2D, His Tag with an affinity constant of 0.17 μM as determined in SPR assay (Biacore T200).
Description	The expressions of both RAET1E2 transcripts and protein can be found in different tumor cells and tissues. ULBP-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.12 kDa and the accession number is Q8TD07-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q8TD07-1
Construction	His31-Asp225
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	ULBP4, RL-4, retinoic acid early transcript 1E, RAET1E2, NKG2DL4, N2DL-4, LETAL, bA350J20.7
Research Background	UL16-binding proteins (ULBPs) are markers of cellular stress which are upregulated on the surface of virus-infected and tumor cells. ULBPs are expressed by a variety of leukemias, carcinomas, melanomas, and tumor cell lines.ULBP4 is associated with higher levels of CD8+/NKG2D+ lymphocytes infiltrating the carcinoma and is a prognosticator of improved survival.

Chemical Properties

Molecular Weight

49.12 kDa (Predicted); 60-70 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.